Thin Melanomas
نویسندگان
چکیده
منابع مشابه
Striking increase of thin melanomas contrasts with stable incidence of thick melanomas.
OBJECTIVE The aim of this study was to analyze the temporal evolution of melanoma incidence in the department of the Bas-Rhin, France, and to study the evolution of tumor thickness. DESIGN Retrospective study including all histologically proven melanomas recorded at the cancer registry of the department of the Bas-Rhin between January 1980 and December 1992 and at the Cutaneous Histopathology...
متن کاملPrognostic significance of tyrosinase expression in sentinel lymph node biopsy for ultra-thin, thin, and thick melanomas.
BACKGROUND Investigate if the tyrosinase mRNA expression may be predictive of the outcome on ultra-thin, thin, and thick melanoma patients. AIM In our study, we sought to correlate tyrosinase mRNA expression to the outcome in a group of 71 patients with thick, thin and ultra-thin melanomas. MATERIALS AND METHODS 71 patients with melanomas underwent a SLNB (sentinel lymph node biopsy) at the...
متن کاملSentinel node biopsy for thin melanomas: which patients should be considered?
BACKGROUND As the incidence of melanoma increases, thin melanomas are being diagnosed at an increasingly frequent rate. Currently available prognostic factors are limited in their ability to reliably discriminate which patients will manifest regional nodal metastasis and would be identified early through sentinel node biopsy. METHODS We summarized our experience with sentinel node biopsy for ...
متن کاملThin primary cutaneous melanomas: associated detection patterns, lesion characteristics, and patient characteristics.
BACKGROUND Public awareness and education may lead to the detection of thinner melanomas, which may result in a decrease in morbidity and mortality rates. Which detection patterns, lesion, and patient characteristics are associated with early detection? METHODS Using the University of Michigan prospective melanoma database, the detection patterns, lesion characteristics, and patient character...
متن کاملThin and thick primary cutaneous melanomas reveal distinct patterns of somatic copy number alterations
Cutaneous melanoma is one of the most aggressive type of skin tumor. Early stage melanoma can be often cured by surgery; therefore current management guidelines dictate a different approach for thin (<1mm) versus thick (>4mm) melanomas. We have carried out whole-exome sequencing in 5 thin and 5 thick fresh-frozen primary cutaneous melanomas. Unsupervised hierarchical clustering analysis of soma...
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ژورنال
عنوان ژورنال: Annals of Surgery
سال: 2003
ISSN: 0003-4932
DOI: 10.1097/01.sla.0000090446.63327.40